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    • Home
    • Side Effect Data
    • Incident Rate
    • Dealing With Side Effects
      • HELP! What do I do?
      • Recovery Protocol
      • Food, Supplements, Other
      • Help With Anorexia
    • Reporting
    • Resources
    • Grief Support
Pet Advocare
  • Home
  • Side Effect Data
  • Incident Rate
  • Dealing With Side Effects
    • HELP! What do I do?
    • Recovery Protocol
    • Food, Supplements, Other
    • Help With Anorexia
  • Reporting
  • Resources
  • Grief Support

Dealing with Anorexia

Loss of appetite (inappetence and anorexia) is one of the most challenging side effects of Librela® / Beransa® or Solensia®. Your pet may be refusing even their favorite foods and treats making it hard to provide them with adequate nutrition. Loss of appetite is cognitive while the hunger sensation is physical. They may retain the physical sensation of hunger yet lack the cognitive impulse to eat. When you give them several food options at once yet they still look at you with hungry eyes it is both heartbreaking and terrifying. What they eat one day they will not eat the next making every meal a challenge. 


Trial and error is the best course of action.  Do your best to avoid foods that are known to be problematic, but you may need to use favorite, less-than-ideal-foods to entice them to eat. Be careful not to cause further digestive disruption. Hand feeding can help, also holding their dish at shoulder height and assisting them to locate and pick up the food. In addition to lack of appetite, reported side effects include spatial awareness, digestive tract distress, and fatigue which may hinder their ability to eat, chew, and swallow.  For suggestions on food visit our page:  https://petadvocare.com/food

Sad dog refusing his food because he has anorexia after receiving Librela® / Beransa® or Solensia®

What to know about pharmaceutical appetite stimulants

Primary considerations with Librela® / Beransa® or Solensia® in the system

1. Librela/Solensia was not tested for interactions with these pharmaceuticals.


2. Side effects of appetite stimulants are similar to side effects of Librela/Solensia, therefore it is another roll of the dice to introduce a substance that could further effect – and/or compromise - the same areas of your pets system. 


 Reference: https://www.petmd.com/dog/nutrition/appetite-stimulants-dogs 

1. Mirtazapine

Mirtazapine is a common drug prescribed to dogs and cats who have a decreased appetite due to conditions that make them feel queasy (such as kidney disease or cancer) or medications (such as chemotherapy).

Mirtazapine was initially developed as an antidepressant in humans. However, it was found that weight gain and increased appetite were side effects, which is why it is often used in pets as an appetite stimulant.

Side effects: 

· vocalization 

· agitation

· vomiting

· incoordination while walking

· restlessness

· muscle tremors

· increased salivation

· sleepiness 

These signs may indicate serotonin syndrome and a need for dose reduction, so please contact your veterinarian if these signs are noted.

2. Maropitant (Cerenia®)

Not technically an appetite stimulant, but it’s an anti-nausea medication and, as such, may help improve a pet’s appetite. 

Often, pets that won’t eat are feeling nauseous even if they do not actually vomit. Antinausea medications can be useful to help them eat more consistently. Other antinausea medications your vet may recommend include ondansetron and meclizine. 

Side effects: 

· Decreased energy level (lethargy) or sedation

· Decreased appetite and weight loss

· Diarrhea

· Incoordination

· Excessive drooling

· Vomiting or retching

· Trembling or muscle tremors

3. Entyce® (Capromorelin)

On the U.S. market in 2017, Entyce® is a ghrelin receptor agonist, meaning it increases the production of growth hormone signaling to the brain to stimulate the appetite. This makes the dog feel hungry.

IMPORTANT SAFETY INFORMATION: ENTYCE® (capromorelin oral solution) is for use in dogs only. Do not use in breeding, pregnant or lactating dogs. Use with caution in dogs with hepatic dysfunction or renal insufficiency. Adverse reactions in dogs may include diarrhea, vomiting, polydipsia, and hypersalivation.

· Diarrhea

· Vomiting

· Drooling

· Belly pain

· Nausea

· Flatulence

· Increased thirst

· Lack of energy

Additional side effects of Elura® in cats may include:

· Loss of appetite

· Changes in behavior

· Anemia (low red blood cell count)

· Dehydration

Signs of Entyce® overdoses in dogs include drooling, red or swollen paws, liver damage, and pale skin or gums. Cats who receive overdoses of Elura® may experience vomiting, drooling, and lethargy.

Alternatives to pharmaceuticals for appetite stimulation

Dog receiving acupuncture treatment for appetite stimulation to combat anorexia after Librela

Acupuncture

 while it cannot cure a condition it is known to reduce pain, inflammation, and nausea. Dogs with decreased appetites due to medical conditions such as diabetes, kidney or liver failure, inflammation of the pancreas, or hormonal conditions such as Addison’s disease, are known to benefit and have an increase in appetite after acupuncture sessions. There is an appetite acupuncture point on the dog’s nose.  .

Dog holding bottle of CBD to aide appetite stimulation in response to anorexia after Librela

CBD

 CBD may be able to support wellness that encourages your dog to fill its belly again. These potential CBD benefits may support a healthy appetite: 

· Promotes feelings of calm and ease – CBD potentially promotes feelings of relaxation and calmness. If stress is causing your dog to ignore its meals, CBD may help with those emotional disturbances.


· Eases joint stiffness – CBD may help with joint stiffness and discomfort due to an active lifestyle (in humans and dogs). If joint discomfort causes your dog’s weakened appetite, you can give them CBD in the form of a digestible chew or as an oil rubbed directly on the offending joints. 


· Aids healthy digestion – Stomach discomfort can certainly lead to a poor appetite, but CBD treats may facilitate your dog’s digestion and support a healthy bowel. 


If your dog is shunning its food bowl due to stress, sadness, joint stiffness or an upset stomach, try incorporating CBD treats or other products into its daily routine. Giving your dog an appetite stimulation supplement in the form of CBD tablets or topicals can help your pet experience increased appetite. 

https://zebracbd.com/blogs/cbd-dog-blog/how-to-stimulate-a-dogs-appetite-with-cbd 

Food Suggestions to Help Spur Appetite

Dog not eating his food because he has the side effect of anorexia after receiving Librela

Boiled Chicken or Other Special Treats:

For a sick or geriatric dog that’s picky about eating, one of the easiest (and most affordable) options to try is tempting them to eat chicken. When giving your dog chicken, make sure it’s plain (with no seasonings or spices), skinless, and boneless. For this reason avoid the rotisserie chickens at the grocery store deli. 

Bone broth and rice

 Simple, easy on the digestion, filling and bone broth provides vital nutrients. Serving it warm is also helpful. Bone broth added to anything can help this situation. 

Pumpkin puree

Easy on the tummy so if stomach discomfort is an issue this is a good choice. 

Crushed up liver treats

 Freeze-dried liver treats (like Stella & Chewy brand) can be crushed up into a powder and sprinkled on food. 

Newman’s Own Jerky Treats

Many dogs love this treat and it has a strong enough smell it may get them to notice. Easy to tear into small pieces and top off a bowl of food. Or even bury into soft food the dog has to eat in order to get to the treat. 

Anorexia: a serious side effect of Librela and Solensia.

Baby food

The ones made with turkey or ham. Smooth consistency, basic ingredients. 

Eggs and other proteins

Add some bone broth and mix up in a food processor.

Graham crackers

This is an odd one, and only cautionary because of the sugar, but some dogs really like these. You can use them to spur the appetite and then offer a more substantial meal. 

Canned (or cooked) fish

From the human food aisle. Alaskan salmon packed in water or olive oil is good for dogs.  Avoid packed with lemon or seasoning.  Sardines are a great source of Omega3's and fatty acids to help with skin ailments.  Often the smellier the better to get an appetite piqued. 

SYRINGE FEEDING

If your pet has not eaten consistently and you need a syringe that can handle more than liquid, this product comes in a syringe with a good sized cylinder and a nice large opening at the tip. It is also easier to depress with a single hand than most cheap medical syringes. 

Link to product on Amazon

Librela side effects.  Solensia Side effects.  Beransa side effects. 


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Tens of thousands of reported cases.

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